Our
lab is interested in questions at the interface of physics and biology.
We use a number of experimental techniques from molecular microbiology
as well as computational methods to elucidate physical models of
biological phenomena. Beyond these fundamental questions, we also have
applied efforts to design new technologies for clinical, forensic, and
environmental sampling. Some ongoing projects include:
- Measurement of the basal error rate of protein translation and the error spectrum
- Studying the population dynamics of phage/host relationship as a model system for selective pressure and evolution
- Design
of a rapid enrichment technology for sampling polymicrobial communities
without the need for culturing or downstream sequencing
- Development
of computational methods for addressing the complexities of whole
genome sequencing of novel environmental isolates and/or communities
- High
throughput genetic screening for the identification of novel gene
function relationships in eukaryotes that enable opportunistic infection
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