Materials - Week 1/2

Microbiology by the numbers editorial, Nature 9, 628(2011)

Next-generation sequencing transforms today's biology,S.C.Schuster, Nature Methods 5, 16-18 (2008)

Handout 1 - Cell/Modeling basics, biological numbers for estimating

Handout 2 - Timeline of Genetics/Genomics milestones

Model Organisms - a historical perspective, B.Muller and U.Grossniklaus, J.Proteomics 73, 2054-2063 (2010)

Materials - Week 3

Homework 1

Measurement of Single-cell dynamics, D.G.Spiller, C.D.Wood, D.A.Rand and M.R.H.White, Nature 465, 736-745 (2010)

Single-Cell Microbiology:Tools, Technologies, and Applications, B.F.Brehm-Stecher and E.A.Johnson, Micro.Molecul.Biol.Rev. 68, 538-559 (2004)

Next-generation DNA Sequencing, J.Shendure and H.Li, Nat.Biotech. 26, 1135-1145 (2008)

Materials - Week 4

Cell Commuters Avoid Delays, L.Mirny, Nature Physics 4, 93-95 (2008)

Facilitated diffusion in chromatin lattices: mechanisticdiversity and regulatory potential, M.Kampmann, Mol.Micro. 57, 889-899 (2005)

Homework 2

Materials - Week 5/6

Unconventional lift-generating mechanisms in free-flying butterflies, R. B. Srygley and A. L. R. Thomas, Nature 420, 660-664 (2002)

Life Depends upon Two Kinds of Water, P.Wiggins, PLOS One, e1406 (2008)

Materials - Week 7

Interfaces and the driving force of hydrophobic assembly, D.Chandler, Nature 437, 640-647 (2005)

Principles of selective ion transport in channels and pumps, EGouaux and R.Mackinnon, Science, 310, 1461-1465 (2005)

Materials - Week 8

Macromolecules that prefer their membranes curvy K.C.Haung and K.S.Ramamurthi, Molecular Microbiology 67, 822-832 (2010)

How proteins produce cellular membrane curvature, J.Zimmerberg and M.M/Koslov, Nature Rev. Mol.Cell Biology, 7, 9-19 (2006)

Midterm Due 10-28-2011

Materials - Week 9

Optical traps for single molecule biophysics: a primer T.T.Perkins, Laser and Photon Rev. 3, 203-220 (2009)

Materials - Week 11

Sequence logos: a new way to display consensus sequences T.D.Schneider and R.M.Stephens, Nuc.Acids.Res.. 18, 6097 (1990)

Pitfalls and Practice of Luria-Delbrück Fluctuation Analysis: A Review W.S.Kendall and P.Frost, Cancer Res.. 48, 1060-1065 (1988)

Materials - Week 12

Molecular clocks: four decades of evolution S.Kumar, Nature Rev. Genetics. 6, 654 (2005)

Articles of Interest

What does physics have to do with cancer?, F.Michor, J.Liphardt, M.Ferrari, and J.Widom, Nat.Rev.Cancer 11, 657-670 (2011)